Article
Promoter polymorphisms of the PCA3 gene are not associated with its overexpression in prostate cancer patients.
Journal of genetics - 1 Jan 2020
Arámbula-Meraz Eliakym, Irigoyen-Arredondo Martín, Cedano-Prieto Dora, Romo-Martínez Enrique, Luque-Ortega Fred, Picos-Cárdenas Verónica, Alvarez-Arrazola Marco, García-Magallanes Noemí
Abstract excerpt
In male, the prostate cancer (PCa) is one of the most frequent neoplasias and the second cause of cancer deaths worldwide. In 2015, more than 6000 men died in Mexico due to this disease. In this regard, prostate cancer associated gene 3 (PCA3) has become an interesting target in PCa as is found highly overexpressed. Moreover, TAAA tandem repeats have been suggested to be associated with the regulation of PCA3...
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