Article
The -786T>C promoter polymorphism of the NOS3 gene is associated with prostate cancer progression.
BMC cancer - 29 Sept 2008
Marangoni Karina, Araújo Thaíse G, Neves Adriana F, Goulart Luiz R
Abstract excerpt
BACKGROUND: There is no biological or epidemiological data on the association between NOS3 promoter polymorphisms and prostate cancer. The polymorphisms in the promoter region of NOS3 gene may be responsible for variations in the plasma NO, which may promote cancer progression by providing a selective growth advantage to tumor cells by angiogenic stimulus and by direct DNA damage. METHODS: This study aimed...
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