Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations.

doi:10.1002/ajmg.b.32805

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Article

Genome-wide admixture mapping of DSM-IV alcohol dependence, criterion count, and the self-rating of the effects of ethanol in African American populations.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2021

Lai Dongbing, Kapoor Manav, Wetherill Leah, Schwandt Melanie, Ramchandani Vijay A, Goldman David, Chao Michael, Almasy Laura, Bucholz Kathleen, Hart Ronald P, Kamarajan Chella, Meyers Jacquelyn L, Nurnberger John I, Tischfield Jay, Edenberg Howard J, Schuckit Marc, Goate Alison, Scott Denise M, Porjesz Bernice, Agrawal Arpana, Foroud Tatiana

Abstract excerpt

African Americans (AA) have lower prevalence of alcohol dependence and higher subjective response to alcohol than European Americans. Genome-wide association studies (GWAS) have identified genes/variants associated with alcohol dependence specifically in AA; however, the sample sizes are still not large enough to detect variants with small effects. Admixture mapping is an alternative way to identify alcohol...

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PMID: 32652861
DOI: 10.1002/ajmg.b.32805
PMCID: PMC9376735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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