Article
Enhanced mating-type switching and sexual hybridization in heterothallic yeast Yarrowia lipolytica.
FEMS yeast research - 1 Mar 2020
Han Changpyo, Kwon Heeun, Park Gyuyeon, Jang Minjeong, Lee Hye-Jeong, Seo Sunghwa, Kwon Mincheol, Jeon Wooyoung, Lee Heeseok, Lee Hongweon, Ahn Jungoh
Abstract excerpt
Yarrowia lipolytica is a non-conventional, heterothallic, oleaginous yeast with wide range of industrial applications. Increasing ploidy can improve advantageous traits for industrial applications including genetic stability, stress resistance, and productivity, but the construction of knockout mutant strains from polyploid cells requires significant effort due to the increased copy numbers of target genes. The...
Topics
- Genes, Mating Type, Fungal
- Genetic Engineering
- Genome, Fungal
- Haploidy
- Homologous Recombination
- Hybridization, Genetic
- Phenotype
- Ploidies
- Yarrowia
