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Article

Stability in effects of different smoking-related polygenic risk scores over age and smoking phenotypes.

Drug and alcohol dependence - 1 Sept 2020

Deutsch Arielle R, Selya Arielle S

Abstract excerpt

PURPOSE: Polygenic risk scores (PRSs) for smoking behavior largely fail to consider the demonstrated developmental change in genetic influence over age and stage of smoking behaviors. Additionally, few studies have examined how stage-specific smoking PRSs (e.g. for initiation vs. smoking heaviness) generalize to other stages of risk. The current study examines the stability of PRS effects over age, and how...

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Identifiers

PMID: 32645681
DOI: 10.1016/j.drugalcdep.2020.108154
PMCID: PMC7423706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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