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Article

Ex vivo assessment of targeted therapies in a rare metastatic epithelial-myoepithelial carcinoma.

Neoplasia (New York, N.Y.) - 1 Sept 2020

Mäkelä Rami, Arjonen Antti, Suryo Rahmanto Aldwin, Härmä Ville, Lehtiö Janne, Kuopio Teijo, Helleday Thomas, Sangfelt Olle, Kononen Juha, Rantala Juha K

Abstract excerpt

Epithelial-myoepithelial carcinoma (EMC) is a rare subtype of salivary gland neoplasms. Since the initial description of the cancer, just over 300 cases have been reported. EMCs occupy a biphasic cellular differentiation-state defined by the constitution of two cell types representing epithelial and myoepithelial lineages, yet the functional consequence of the differentiation-state heterogeneity with respect to...

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Identifiers

PMID: 32645560
DOI: 10.1016/j.neo.2020.06.007
PMCID: PMC7341452

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