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Article

Clinical characteristics and treatment outcomes of HER2 mutation and HER2 fusion in 22 patients with advanced breast cancer.

Thoracic cancer - 1 Dec 2023

Mu Yuxin, Meng Yanchun, Du Yiqun, Liu Xiaojun, Zhang Jian

Abstract excerpt

BACKGROUND: The clinical characteristics and efficacy of human epidermal growth factor receptor-2 (HER-2)-directed agents against HER2 mutations and HER2 fusions in breast cancer are obscure due to their low frequency. METHODS: We conducted a retrospective study in patients with advanced breast cancer harboring HER2 mutations and/or HER2 fusions between January 1, 2017 and January 1, 2021. RESULTS: Among a total...

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Identifiers

PMID: 37863840
DOI: 10.1111/1759-7714.15130
PMCID: PMC10693943

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