Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationships between substance use and insomnia

2 Jul 2020

Abstract excerpt

BACKGROUND: Poor sleep quality and insomnia have been associated with the use of tobacco, alcohol, and cannabis, but it is unclear if there is a causal link. In this Mendelian Randomization (MR) study we examine if insomnia causes substance use and/or if substance use causes insomnia. METHODS: MR uses summary effect estimates from a genome-wide association study (GWAS) to create a genetic instrumental variable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Associations and Epidemiology
Share to Sleep and related disorders
Share to Substance Abuse Treatment and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32634714
DOI: 10.1016/j.drugalcdep.2020.108151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationships between substance use and insomniaPMID 32634714Read ↗

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.Semantic proximity Read ↗

The relationship between alcohol- and sleep-related traits: Results from polygenic risk score and Mendelian randomization analyses.Semantic proximity Read ↗

Characterisation of the genetic relationship between the domains of sleep and circadian-related behaviours with substance use phenotypes.Semantic proximity Read ↗

Using Mendelian randomization to explore the gateway hypothesis: possible causal effects of smoking initiation and alcohol consumption on substance use outcomes.Semantic proximity Read ↗

Genetic liability to insomnia and substance use disorders in patients with bipolar disorderSemantic proximity Read ↗

The bidirectional causal relationships of insomnia with five major psychiatric disorders: A Mendelian randomization studySemantic proximity Read ↗

The Causal Effects of Insomnia on Bipolar Disorder, Depression, and Schizophrenia: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Exploration of Genetic Liability to Insomnia and Substance Use Disorders in Patients With Bipolar Disorder.Semantic proximity Read ↗

Mendelian randomization highlights insomnia as a risk factor for pain diagnoses.Semantic proximity Read ↗

Leveraging Genomic Data to Examine the Causal Impact of Alcohol, Tobacco, Cannabis, and Opioid Use on Biological and Cognitive Ageing.Semantic proximity Read ↗

Association between alcohol consumption and sleep traits: observational and mendelian randomization studies in the UK biobank.Semantic proximity Read ↗

Genome-wide association analysis of insomnia using data from Partners Biobank.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.