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Article

Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization.

Addiction biology - 1 Jan 2021

Treur Jorien L, Demontis Ditte, Smith George Davey, Sallis Hannah, Richardson Tom G, Wiers Reinout W, Børglum Anders D, Verweij Karin J H, Munafò Marcus R

Abstract excerpt

Attention-deficit hyperactivity disorder (ADHD) has consistently been associated with substance use, but the nature of this association is not fully understood. To inform intervention development and public health messages, a vital question is whether there are causal pathways from ADHD to substance use and/or vice versa. We applied bidirectional Mendelian randomization, using summary-level data from the largest...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31733098
DOI: 10.1111/adb.12849
PMCID: PMC7228854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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