Article
Molecular analyses of glioblastoma stem-like cells and glioblastoma tissue.
PloS one - 1 Jan 2020
Wallenborn Marco, Xu Li-Xin, Kirsten Holger, Rohani Leili, Rudolf Daniela, Ahnert Peter, Schmidt Christian, Schulz Ronny M, Richter Mandy, Krupp Wolfgang, Mueller Wolf, Johnson Adiv A, Meixensberger Jürgen, Holland Heidrun
Abstract excerpt
Glioblastoma is a common, malignant brain tumor whose disease incidence increases with age. Glioblastoma stem-like cells (GSCs) are thought to contribute to cancer therapy resistance and to be responsible for tumor initiation, maintenance, and recurrence. This study utilizes both SNP array and gene expression profiling to better understand GSCs and their relation to malignant disease. Peripheral blood and primary...
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