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Article

Dab2 gene variant is associated with increased coronary artery disease risk in Chinese Han population.

Medicine - 2 Jul 2020

Wang Yinghong, Wang Yongtao, Adi Dilare, He XiaoDong, Liu Fen, Abudesimu Asiya, Fu Zhenyan, Ma Yitong

Abstract excerpt

Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, we aimed to investigate the association between Dab2 single-nucleotide polymorphisms (SNPs) and CAD in Chinese Han and Uyghur populations.We performed a case-control...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32629690
DOI: 10.1097/MD.0000000000020924
PMCID: PMC7337449

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