Article
Association study of genetic variants at TTC32-WDR35 gene cluster with coronary artery disease in Chinese Han population.
Journal of clinical laboratory analysis - 1 Feb 2021
Xu Ying, Zhuo Yang, Ye Mengliang, Li Mengmeng, Tang Xiaojun, Zhou Li
Abstract excerpt
BACKGROUND: TTC32-WDR35 gene cluster has been genome-wide significantly associated with coronary artery disease (CAD). However, the common variants in this region contributing to CAD risk remain elusive. METHODS: We performed a case-control study enrolling 935 CAD cases and 935 age-sex-frequency-matched controls from unrelated southwest Chinese Han population. Five variants were determined by TaqMan assay....
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