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Article

Genetic polymorphism of the Dab2 gene and its association with Type 2 Diabetes Mellitus in the Chinese Uyghur population.

PeerJ - 1 Jan 2023

Li Yan-Peng, Adi Dilare, Wang Ying-Hong, Wang Yong-Tao, Li Xiao-Lei, Fu Zhen-Yan, Liu Fen, Aizezi Aibibanmu, Abuzhalihan Jialin, Gai Mintao, Ma Xiang, Li Xiao-Mei, Xie Xiang, Ma YiTong

Abstract excerpt

Objective: The human Disabled-2 (Dab2) protein is an endocytic adaptor protein, which plays an essential role in endocytosis of transmembrane cargo, including low-density lipoprotein cholesterol (LDL-C). As a candidate gene for dyslipidemia, Dab2 is also involved in the development of type 2 diabetes mellitus(T2DM). The aim of this study was to investigate the effects of genetic variants of the Dab2 gene on the...

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Share to Adaptor Proteins, Signal Transducing
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Diabetes Mellitus, Type 2

Share to East Asian People

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 37361044
DOI: 10.7717/peerj.15536
PMCID: PMC10290452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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