Article
A role for human leucocyte antigens in the susceptibility to SARS-Cov-2 infection observed in transplant patients.
International journal of immunogenetics - 1 Aug 2020
Poulton Kay, Wright Paul, Hughes Pamela, Savic Sinisa, Welberry Smith Matthew, Guiver Malcolm, Morton Muir, van Dellen David, Tholouli Eleni, Wynn Robert, Clark Brendan
Abstract excerpt
We analysed data from 80 patients who tested positive for SARS-CoV-2 RNA who had previously been HLA typed to support transplantation. Data were combined from two adjacent centres in Manchester and Leeds to achieve a sufficient number for early analysis. HLA frequencies observed were compared against two control populations: first, against published frequencies in a UK deceased donor population (n = 10,000)...
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