Article
Regulation of ABO blood group antigen expression by miR-331-3p and miR-1908-5p during hematopoietic stem cell differentiation.
Stem cells (Dayton, Ohio) - 1 Oct 2020
Kronstein-Wiedemann Romy, Nowakowska Paulina, Milanov Peter, Gubbe Knut, Seifried Erhard, Bugert Peter, Chavakis Triantafyllos, Tonn Torsten
Abstract excerpt
The ABO blood group system is the most important factor in clinical transfusion medicine and is implicated in a number of human diseases. ABO antigens are not confined to red blood cells (RBCs) and are widely expressed in a variety of human cells and tissues. To date, many alleles with variant ABO expression have been identified and in many cases traced to one of the >250 reported genetic variations in the...
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