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Article

c.98 + 3A>G and c.155 + 1G>T splice-site variants in the ABO*B.01 allele lead to weak antigen expression in the Chinese individuals.

Frontiers in immunology - 1 Jan 2026

Zhang Jingjing, Ying Yanling, Hong Xiaozhen, Zhu Faming

Abstract excerpt

Background: Many variants within the ABO gene across multiple subtypes have been identified. These variants are located in the coding region, the erythroid-specific regulatory element region of intron 1, splice sites, and other non-coding regions. However, data regarding the functional analysis of these variants remain limited. In this study, we analyzed the function of two splice-site variants in ABO subtypes....

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Identifiers

PMID: 42099606
DOI: 10.3389/fimmu.2026.1739842
PMCID: PMC13143704

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ABO

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