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Article

Serology and molecular genetic analysis of weakened expression of ABO blood group antigens in Chinese pediatric population.

Blood transfusion = Trasfusione del sangue - 1 Jan 2026

Ren Qian, Li Jinfeng, Li Chunmiao, Liu Xingli, Ma Xiaolin

Abstract excerpt

BACKGROUND: The ABO blood group system is vital for red blood cell antigens. Weakened expression of ABO antigens often leads to misidentification of blood types, challenging transfusion safety. MATERIALS AND METHODS: Blood samples from 44 cases underwent serological analysis using microcolumn agglutination and tube tests. To investigate genetic variations, we sequenced the promoter region and exons 1-7 of the ABO...

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Identifiers

PMID: 42008351
DOI: 10.2450/BloodTransfus.1237
PMCID: PMC13368444

Genes

ABO

Variants

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