Article
Truncated glycosyltransferase coding regions in novel ABO alleles give rise to weak A or B blood group expression and discrepant typing results.
Transfusion - 1 Oct 2023
Ricci Hagman Jennifer, Hult Annika K, Hellberg Åsa, Olsson Martin L
Abstract excerpt
BACKGROUND: Correct ABO blood-group matching between donor and patient is crucial for safe transfusions. We investigated the underlying reason causing inconclusive ABO serology in samples referred to our laboratory. STUDY DESIGN AND METHODS: Flow cytometric analysis, ABO genotyping, and sequencing were used to characterize ABO-discrepant blood samples (n = 13). ABO gene variants were inserted in a GFP-containing...
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