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RUNX1 mutation in a patient with myelodysplastic syndrome and decreased erythrocyte expression of blood group A antigen.

Transfusion - 1 Jan 2020

Hayakawa Akira, Sano Rie, Takahashi Yoichiro, Kubo Rieko, Harada Megumi, Omata Masato, Yokohama Akihiko, Handa Hiroshi, Tsukada Junichi, Takeshita Haruo, Tsuneyama Hatsue, Ogasawara Kenichi, Kominato Yoshihiko

Abstract excerpt

BACKGROUND: Loss of blood group ABO antigens on red blood cells (RBCs) is well known in patients with leukemias, and such decreased ABO expression has been reported to be strongly associated with hypermethylation of the ABO promoter. We investigated the underlying mechanism responsible for A-antigen reduction on RBCs in a patient with myelodysplastic syndrome. STUDY DESIGN AND METHODS: Genetic analysis of ABO was...

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PMID: 31840280
DOI: 10.1111/trf.15628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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RUNX1 mutation in a patient with myelodysplastic syndrome and decreased erythrocyte expression of blood group A antigen.PMID 31840280Read ↗

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