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Article

Cell-to-cell expression dispersion of B-cell surface proteins is linked to genetic variants in humans.

Communications biology - 3 Jul 2020

Triqueneaux Gérard, Burny Claire, Symmons Orsolya, Janczarski Stéphane, Gruffat Henri, Yvert Gaël

Abstract excerpt

Variability in gene expression across a population of homogeneous cells is known to influence various biological processes. In model organisms, natural genetic variants were found that modify expression dispersion (variability at a fixed mean) but very few studies have detected such effects in humans. Here, we analyzed single-cell expression of four proteins (CD23, CD55, CD63 and CD86) across cell lines derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32620900
DOI: 10.1038/s42003-020-1075-1
PMCID: PMC7335051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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