Is tumor testing efficiency for Lynch syndrome different in rectal and colon cancer?

doi:10.1016/j.dld.2020.06.002

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Article

Is tumor testing efficiency for Lynch syndrome different in rectal and colon cancer?

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Dec 2020

Marabelli Monica, Gandini Sara, Rafaniello Paola Raviele, Calvello Mariarosaria, Tolva Gianluca, Feroce Irene, Lazzeroni Matteo, Marino Elena, Dal Molin Matteo, Trovato Cristina, Guerrieri-Gonzaga Aliana, Petz Wanda Luisa, Barberis Massimo, Bertario Lucio, Bonanni Bernardo

Abstract excerpt

BACKGROUND: Tumor testing utility in Lynch syndrome (LS) diagnosis is established. AIMS: Analyze the differences between tumor testing efficiency in rectal (RC) and colon cancer (CC). METHODS: We performed immunohistochemistry (IHC) for MisMatch Repair (MMR) proteins (IHC-MMR) and MicroSatellite Instability analysis (MSI) on 482 unselected primary tumors: 320 CCs and 162 RCs. Samples had proficient-IHC,...

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PMID: 32620519
DOI: 10.1016/j.dld.2020.06.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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