Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-375 represses tumor angiogenesis and reverses resistance to sorafenib in hepatocarcinoma

2 Jul 2020

Abstract excerpt

Sorafenib was originally identified as an inhibitor of multiple oncogenic kinases and remains the first-line systemic therapy for advanced hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) have been reported to play critical roles in the initiation, progression, and drug resistance of HCC. In this study, we aimed to identify sorafenib-induced miRNAs and demonstrate their regulatory roles. First, we identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Circular RNAs in diseases
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32616906
DOI: 10.1038/s41417-020-0191-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-375 represses tumor angiogenesis and reverses resistance to sorafenib in hepatocarcinomaPMID 32616906Read ↗

MicroRNA-140-5p Suppresses The PD-L1 Level In Exosomes Derived From Hepatocellular Carcinoma Cells, Thereby Attenuating The Chemoresistance, Autophagy And Stemness Induced By Sorafenib In Hepatocellular CarcinomaSemantic proximity Read ↗

MicroRNA-375: potential cancer suppressor and therapeutic drugSemantic proximity Read ↗

Identification of genes conferring resistance to 5-fluorouracilSemantic proximity Read ↗

Molecular mechanisms of sorafenib action in liver cancer cellsSemantic proximity Read ↗

Hypoxia‐induced miR‐3677‐3p promotes the proliferation, migration and invasion of hepatocellular carcinoma cells by suppressing SIRT5Semantic proximity Read ↗

miR-183-5p attenuates the effect of sorafenib on human hepatocellular carcinoma via inhibiting SOCS6/JAK2/STAT3 pathwaySemantic proximity Read ↗

Y-Box Binding Protein-1 Promotes Epithelial-Mesenchymal Transition in Sorafenib-Resistant Hepatocellular Carcinoma CellsSemantic proximity Read ↗

miR-541 potentiates the response of human hepatocellular carcinoma to sorafenib treatment by inhibiting autophagy.Semantic proximity Read ↗

The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma.Semantic proximity Read ↗

Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular CarcinomaSemantic proximity Read ↗

Targeting PCBP1 Sequentially Represses BAG1 and SOX2/β-catenin Axis to Inhibit HCC Cells Proliferation and Reverse Intrinsic Sorafenib ResistanceSemantic proximity Read ↗

MicroRNA-331 Inhibits Proliferation and Invasion of Melanoma Cells by Targeting Astrocyte-Elevated Gene-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.