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Article

High throughput single cell analysis of mitochondrial heteroplasmy in mitochondrial diseases.

Scientific reports - 2 Jul 2020

Maeda Ryotaro, Kami Daisuke, Maeda Hideki, Shikuma Akira, Gojo Satoshi

Abstract excerpt

Mitochondrial heteroplasmy, which fundamentally means intracellular heterogeneity of mitochondrial DNA (mtDNA), has been measured in a group of cells, regardless of intercellular heterogeneity. Ordinal methods for mitochondrial heteroplasmy cannot discriminate between an intercellular homogenic population composed of cells with similar intracellular heterogeneity for mtDNA and an intercellular heterogenic...

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Identifiers

PMID: 32616755
DOI: 10.1038/s41598-020-67686-z
PMCID: PMC7331593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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