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Article

Drosophila GFAT1 and GFAT2 enzymes encode obligate developmental functions.

Fly - 1 Jan 2000

Chen Po, Visokay Sarah, Abrams John M

Abstract excerpt

Glutamine: fructose-6-phosphate amidotransferase (GFAT) enzymes catalyse the first committed step of the hexosamine biosynthesis pathway (HBP) using glutamine and fructose-6-phosphate to form glucosamine-6-phosphate (GlcN6P). Numerous species (e.g. mouse, rat, zebrafish, chicken) including humans and Drosophila encode two broadly expressed copies of this enzyme but whether these perform redundant, partially...

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Identifiers

PMID: 32615907
DOI: 10.1080/19336934.2020.1784674
PMCID: PMC7714458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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