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Article

A Drosophila melanogaster model of classic galactosemia.

Disease models & mechanisms - 1 Jan 2000

Kushner Rebekah F, Ryan Emily L, Sefton Jennifer M I, Sanders Rebecca D, Lucioni Patricia Jumbo, Moberg Kenneth H, Fridovich-Keil Judith L

Abstract excerpt

Classic galactosemia is a potentially lethal disorder that results from profound impairment of galactose-1-phosphate uridylyltransferase (GALT). Despite decades of research, the underlying pathophysiology of classic galactosemia remains unclear, in part owing to the lack of an appropriate animal model. Here, we report the establishment of a Drosophila melanogaster model of classic galactosemia; this is the first...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20519569
DOI: 10.1242/dmm.005041
PMCID: PMC2931538

Genes

GALT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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