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Article

The influence of coffee intake and genetics on adenosine pathway in rheumatoid arthritis.

Pharmacogenomics - 1 Jul 2020

Soukup Tomáš, Hloch Karel, Doseděl Martin, Tebbens Jurjen Duintjer, Nekvindová Jana, Šembera Štěpán, Veleta Tomáš, Pávek Petr, Barvík Ivan

Abstract excerpt

Aim: We studied the influence of coffee consumption on the therapeutic effect of methotrexate (MTX) in patients with rheumatoid arthritis (RA) sorted according to ADORA2A genotypes. Patients & methods: 82 RA patients were dichotomized according to caffeine intake with a threshold of 700 mg/week. Disease activity score 28 (DAS28) was applied (>3.2: high; <3.2: low or remission). Patients were genotyped using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32615857
DOI: 10.2217/pgs-2020-0042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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