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Article

Polygenic Risk Scores Allow Risk Stratification for Keratinocyte Cancer in Organ-Transplant Recipients.

The Journal of investigative dermatology - 1 Feb 2021

Seviiri Mathias, Law Matthew H, Ong Jue Sheng, Gharahkhani Puya, Nyholt Dale R, Olsen Catherine M, Whiteman David C, MacGregor Stuart

Abstract excerpt

Organ-transplant recipients have an elevated risk of keratinocyte cancers: basal cell carcinoma (BCC) and squamous cell carcinoma. We assessed whether polygenic risk scores (PRSs) generated in nontransplantees from the UK Biobank and 23andMe (13,981 squamous cell carcinoma, 33,736 BCC, and >560,000 controls) can predict keratinocyte cancer risk in an independent organ-transplant recipient cohort. After adjusting...

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Identifiers

PMID: 32615124
DOI: 10.1016/j.jid.2020.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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