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Article

CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis.

The Journal of cell biology - 3 Aug 2020

Sofroni Kostika, Takatsuka Hirotomo, Yang Chao, Dissmeyer Nico, Komaki Shinichiro, Hamamura Yuki, Böttger Lev, Umeda Masaaki, Schnittger Arp

Abstract excerpt

Precise control of cytoskeleton dynamics and its tight coordination with chromosomal events are key to cell division. This is exemplified by formation of the spindle and execution of cytokinesis after nuclear division. Here, we reveal that the central cell cycle regulator CYCLIN DEPENDENT KINASE A;1 (CDKA;1), the Arabidopsis homologue of Cdk1 and Cdk2, partially in conjunction with CYCLIN B3;1 (CYCB3;1), is a key...

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Identifiers

PMID: 32609301
DOI: 10.1083/jcb.201907016
PMCID: PMC7401817

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