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Article

Cyclin-dependent kinase-activating kinases CDKD;1 and CDKD;3 are essential for preserving mitotic activity in Arabidopsis thaliana.

The Plant journal : for cell and molecular biology - 1 Jun 2015

Takatsuka Hirotomo, Umeda-Hara Chikage, Umeda Masaaki

Abstract excerpt

For the full activation of cyclin-dependent kinases (CDKs), not only cyclin binding but also CDK phosphorylation is required. This activating phosphorylation is mediated by CDK-activating kinases (CAKs). Arabidopsis has four genes showing similarity to vertebrate-type CAKs, three CDKDs (CDKD;1-CDKD;3) and one CDKF (CDKF;1). We previously found that the cdkf;1 mutant is defective in post-embryonic development,...

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PMID: 25942995
DOI: 10.1111/tpj.12872

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