Article
The cell cycle controls spindle architecture in Arabidopsis by activating the augmin pathway.
Developmental cell - 18 Nov 2024
Romeiro Motta Mariana, Nédélec François, Saville Helen, Woelken Elke, Jacquerie Claire, Pastuglia Martine, Stolze Sara Christina, Van De Slijke Eveline, Böttger Lev, Belcram Katia, Nakagami Hirofumi, De Jaeger Geert, Bouchez David, Schnittger Arp
Abstract excerpt
To ensure an even segregation of chromosomes during somatic cell division, eukaryotes rely on mitotic spindles. Here, we measured prime characteristics of the Arabidopsis mitotic spindle and built a three-dimensional dynamic model using Cytosim. We identified the cell-cycle regulator CYCLIN-DEPENDENT KINASE B1 (CDKB1) together with its cyclin partner CYCB3;1 as key regulators of spindle morphology in Arabidopsis....
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