Article
Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population.
Journal of reproductive immunology - 1 Sept 2020
Kelemu Tsehayneh, Erlandsson Lena, Seifu Daniel, Hansson Eva, Abebe Markos, Teklu Sisay, Girma Selfu, Traherne James A, Moffett Ashley, Hansson Stefan R
Abstract excerpt
INTRODUCTION: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2-8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate the association...
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