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Article

The Distinct Role of the Extra-Large G Protein ɑ-Subunit XLɑs.

Calcified tissue international - 1 Sept 2020

Wang Yan, Tian Haoming, Chen Xiang

Abstract excerpt

GNAS is one of the most complex gene loci in the human genome and encodes multiple gene products including Gsα, XLαs, NESP55, A/B, and AS transcripts. XLαs, the extra-large G protein ɑ-subunit, is paternally expressed. XLɑs and Gsɑ share the common 2-13 exons with different promoters and first exons. Therefore, XLɑs contains most of the functional domains of Gsα including receptor and effector binding sites. In...

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PMID: 32596800
DOI: 10.1007/s00223-020-00714-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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