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Article

Real world data analysis of next generation sequencing and protein expression in metastatic breast cancer patients.

Scientific reports - 26 Jun 2020

Hempel Dirk, Ebner Florian, Garg Arun, Trepotec Zeljka, Both Armin, Stein Werner, Gaumann Andreas, Güttler Lucia, Janni Wolfgang, DeGregorio Amelie, Hempel Louisa, Milani Valeria

Abstract excerpt

Next generation sequencing (NGS) together with protein expression analysis is back bone of molecularly targeted therapy in precision medicine. Our retrospective study shows our experience with NGS of 324 genes in combination with protein expression in patients with advanced breast cancer (aBC). The primary purpose was to analyze the prevalence of individual genetic alterations combined with protein expression to...

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Identifiers

PMID: 32591580
DOI: 10.1038/s41598-020-67393-9
PMCID: PMC7319999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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