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Article

IGF-1 treatment causes unique transcriptional response in neurons from individuals with idiopathic autism

26 Jun 2020

Abstract excerpt

BACKGROUND: Research evidence accumulated in the past years in both rodent and human models for autism spectrum disorders (ASD) have established insulin-like growth factor 1 (IGF-1) as one of the most promising ASD therapeutic interventions to date. ASD is phenotypically and etiologically heterogeneous, making it challenging to uncover the underlying genetic and cellular pathophysiology of the condition; and to...

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PMID: 32591005
DOI: 10.1186/s13229-020-00359-w

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