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Article

Intestinal dysbiosis in pediatric Crohn's disease patients with IL10RA mutations.

World journal of gastroenterology - 14 Jun 2020

Xue Ai-Juan, Miao Shi-Jian, Sun Hua, Qiu Xiao-Xia, Wang Sheng-Nan, Wang Lin, Ye Zi-Qing, Zheng Cui-Fang, Huang Zhi-Heng, Wang Yu-Huan, Huang Ying

Abstract excerpt

BACKGROUND: Several studies have employed animal models to explore the association between microbiota and interleukin (IL) 10 signaling; however, limited information is available about the human microbiome. AIM: To characterize the microbiome in patients with IL10RA mutations and to explore the association between gut dysbiosis and disease severity. METHODS: Fecal samples were collected from patients who were...

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Identifiers

PMID: 32587451
DOI: 10.3748/wjg.v26.i22.3098
PMCID: PMC7304104

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