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Do gene polymorphism in IL-1β, TNF-α and IL-6 influence therapeutic response in patients with drug refractory epilepsy?

Epilepsy research - 1 Sept 2012

Tiwari Prabhakar, Dwivedi Rekha, Mansoori Nasim, Alam Rizwan, Chauhan Ugam Kumari, Tripathi Manjari, Mukhopadhyay Asok Kumar

Abstract excerpt

PURPOSE: Pro-inflammatory cytokines may play an important pathophysiological role in patients with epilepsy. To understand the role of genes encoding pro-inflammatory cytokines in epilepsy, this study aimed to evaluate the polymorphisms of the promoter regions of IL-1β-511C>T (rs16944), TNF-α-308G>A (rs1800629) and IL-6-174G>C (rs1800795) genes and to look into the interaction between these genes in influencing...

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PMID: 22578659
DOI: 10.1016/j.eplepsyres.2012.04.013

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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