Article
Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single-nucleotide polymorphisms in elite master athletes.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Aug 2020
Crossland Hannah, Piasecki Jessica, McCormick Daniel, Phillips Bethan E, Wilkinson Daniel J, Smith Kenneth, McPhee Jamie S, Piasecki Mathew, Atherton Philip J
Abstract excerpt
Recent large genome-wide association studies (GWAS) have independently identified a set of genetic loci associated with lean body mass (LBM) and handgrip strength (HGS). Evaluation of these candidate single-nucleotide polymorphisms (SNPs) may be useful to investigate genetic traits of populations at higher or lower risk of muscle dysfunction. As such, we investigated associations between six SNPs linked to LBM or...
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