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Article

A LncRNA gene polymorphism (rs1814343) is associated with the risk of coronary artery lesions in southern Chinese Kawasaki disease patients.

The journal of gene medicine - 1 Aug 2023

Chen Wenchao, Chen Shuo, Tian Yan, Liu Yanqing, Chen Cheng, Wang Bingtong, Chen Chongfeng, Liu Fucheng

Abstract excerpt

BACKGROUND: Kawasaki disease (KD) is a multisystemic angiitis, and its most disastrous complication is coronary artery lesions (CALs). Recently, the role of long non-coding RNAs (lncRNAs) in KD has been reported. rs1814343 is a lncRNA, but the relationship between the lncRNA rs1814343 polymorphism and KD risk remains elusive. METHODS: We enrolled 1625 Kawasaki disease patients (583 patients with CAL and 1042...

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PMID: 37097087
DOI: 10.1002/jgm.3514

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