Article
MiR-148b-3p inhibits renal carcinoma cell growth and pro-angiogenic phenotype of endothelial cell potentially by modulating FGF2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2018
Zhang Hui, Ye Qing, Du Zhenfang, Huang Min, Zhang Ming, Tan Huifeng
Abstract excerpt
MicroRNAs (miRNAs) have been implicated in a large number of biological processes such as tumor angiogenesis. MiR-148b-3p has been identified as a tumor suppressor in multiple cancer types and the function of miR-148b-3p in renal carcinoma remains unidentified. In this study, we found that the expression of miR-148b-3p was decreased in renal carcinoma based on GEO analysis and the gain-of-function experiments...
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