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Article

Single Nucleotide Polymorphisms in PPARD Associated with Systemic Lupus Erythematosus in Chinese Populations.

Journal of immunology research - 1 Jan 2020

Qi Yuan-Yuan, Zhai Ya-Ling, Liu Xin-Ran, Zhang Xiao-Xue, Zhao Ya-Fei, Ning Xiang-Hui, Zhao Zhan-Zheng

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by apoptotic clearance deficiency provoking autoimmune responses and leading to multiple organ damage. PPAR-δ, encoded by the PPARD gene, was induced in macrophages promoting the timely disposal of apoptotic cells. Biological studies had provided solid foundation of PPARD involvement in SLE; it is worthwhile to...

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Identifiers

PMID: 32566688
DOI: 10.1155/2020/7285747
PMCID: PMC7281840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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