Article
Primary tumor characteristics and next-generation sequencing mutations as biomarkers for melanoma immunotherapy response.
Pigment cell & melanoma research - 1 Nov 2020
Loo Kimberly, Gauvin Gabrielle, Soliman Iman, Renzetti Madelyn, Deng Mengying, Ross Eric, Luo Biao, Wu Hong, Reddy Sanjay, Olszanski Anthony J, Farma Jeffrey M
Abstract excerpt
INTRODUCTION: Considerable advances in melanoma have been realized through immunotherapy. The principal aim was to determine whether primary tumor characteristics or next-generation sequencing (NGS) could serve as markers of immunotherapy response. METHODS AND RESULTS: The study cohort consisted of 67 patients who received immunotherapy for recurrent or metastatic melanoma and for whom primary tumor biopsies and...
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