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Using brain organoids to understand Zika virus-induced microcephaly

14 Mar 2017

Abstract excerpt

ABSTRACT Technologies to differentiate human pluripotent stem cells into three-dimensional organized structures that resemble in vivo organs are pushing the frontiers of human disease modeling and drug development. In response to the global health emergency posed by the Zika virus (ZIKV) outbreak, brain organoids engineered to mimic the developing human fetal brain have been employed to model ZIKV-induced...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28292840
DOI: 10.1242/dev.140707

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