Article
Measles virus and rinderpest virus divergence dated to the sixth century BCE.
Science (New York, N.Y.) - 19 Jun 2020
Düx Ariane, Lequime Sebastian, Patrono Livia Victoria, Vrancken Bram, Boral Sengül, Gogarten Jan F, Hilbig Antonia, Horst David, Merkel Kevin, Prepoint Baptiste, Santibanez Sabine, Schlotterbeck Jasmin, Suchard Marc A, Ulrich Markus, Widulin Navena, Mankertz Annette, Leendertz Fabian H, Harper Kyle, Schnalke Thomas, Lemey Philippe, Calvignac-Spencer Sébastien
Abstract excerpt
Many infectious diseases are thought to have emerged in humans after the Neolithic revolution. Although it is broadly accepted that this also applies to measles, the exact date of emergence for this disease is controversial. We sequenced the genome of a 1912 measles virus and used selection-aware molecular clock modeling to determine the divergence date of measles virus and rinderpest virus. This divergence date...
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