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Article

ALCAM (CD166) as a gene expression marker for human mesenchymal stromal cell characterisation

14 Mar 2020

Abstract excerpt

BACKGROUND: Human mesenchymal stromal cells (MSCs) phenotypically share their positive expression of the International Society for Cell and Gene Therapy (ISCT) markers CD73, CD90 and CD105 with fibroblasts. Fibroblasts are often co-isolated as an unwanted by-product from biopsy and they can rapidly overgrow the MSCs in culture. Indeed, many other surface markers have been proposed, though no unique MSC specific...

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PMID: 32550557
DOI: 10.1016/j.gene.2020.100031

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