Article
Identification of Pathways in Liver Repair Potentially Targeted by Secretory Proteins from Human Mesenchymal Stem Cells.
International journal of molecular sciences - 9 Jul 2016
Winkler Sandra, Hempel Madlen, Brückner Sandra, Tautenhahn Hans-Michael, Kaufmann Roland, Christ Bruno
Abstract excerpt
BACKGROUND: The beneficial impact of mesenchymal stem cells (MSC) on both acute and chronic liver diseases has been confirmed, although the molecular mechanisms behind it remain elusive. We aim to identify factors secreted by undifferentiated and hepatocytic differentiated MSC in vitro in order to delineate liver repair pathways potentially targeted by MSC. METHODS: Secreted factors were determined by protein...
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