Article
Phenotypic characterization of distinct human bone marrow-derived MSC subsets.
Annals of the New York Academy of Sciences - 1 Sept 2009
Bühring Hans-Jörg, Treml Sabrina, Cerabona Flavianna, de Zwart Peter, Kanz Lothar, Sobiesiak Malgorzata
Abstract excerpt
Very recently, we identified two distinct mesenchymal stem cell (MSC) subsets in primary bone marrow (BM) that differ in their expression pattern (CD271(bright)MSCA-1(dim)CD56(+) and CD271(bright)MSCA-1(bright)CD56(-)) and morphology as well as in their clonogenic and differentiation capacity. Here we analyzed the cell surface antigen expression in these subsets in more detail and compared the profiles with the...
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