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Article

IGF-1 and cardiometabolic diseases: a Mendelian randomisation study.

Diabetologia - 1 Sept 2020

Larsson Susanna C, Michaëlsson Karl, Burgess Stephen

Abstract excerpt

AIMS/HYPOTHESIS: Abnormal serum IGF-1 levels are associated with an increased risk of type 2 diabetes and cardiovascular disease. However, the causal role of IGF-1 levels within the normal range in cardiometabolic disease remains unclear. We employed Mendelian randomisation to explore the associations between genetically predicted serum IGF-1 levels and cardiometabolic diseases. METHODS: Serum IGF-1 levels were...

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Identifiers

PMID: 32548700
DOI: 10.1007/s00125-020-05190-9
PMCID: PMC7406523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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