Article
Going beyond RGD: screening of a cell-adhesion peptide library in 3D cell culture.
Biomedical materials (Bristol, England) - 31 Aug 2020
Sarwat Mariah, Surrao Denver C, Huettner Nick, St John James A, Dargaville Tim R, Forget Aurelien
Abstract excerpt
In tissue engineering, cell-adhesion peptides (CAPs) such as the ubiquitous arginine-glycine-aspartic acid (RGD) sequence have allowed the functionalization of synthetic materials to mimic macromolecules of the extracellular matrix (ECM). However, the variety of ECM macromolecules makes it challenging to reproduce all of the native tissue functions with only a limited variety of CAPs. Screening of libraries of...
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