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Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells.

Molecular cancer therapeutics - 1 Oct 2004

Mikawa Masahito, Wang Henry, Guo Linlang, Liu Ruiwu, Marik Jan, Takada Yoshikazu, Lam Kit, Lau Derick

Abstract excerpt

Using the "one-bead one-peptide" combinatorial technology, a library of random cyclic octapeptides and nonapeptides, consisting of natural and unnatural amino acids, was synthesized on polystyrene beads. This library was used to screen for peptides that promoted attachment and proliferation of bronchioloalveolar carcinoma cells (H1650), employing a "cell growth on bead" assay. Consensus peptide sequences of...

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PMID: 15486200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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