Article
Effects of RAGE Gene Polymorphisms on the Risk and Progression of Hepatocellular Carcinoma.
Medicine - 1 Aug 2015
Su Shih-Chi, Hsieh Ming-Ju, Chou Ying-Erh, Fan Wen-Lang, Yeh Chao-Bin, Yang Shun-Fa
Abstract excerpt
Hepatocellular carcinoma (HCC) is a common malignancy of the liver, whose heterogeneous incidence reflects genetic variations among individuals in the main risk factors. The receptor for advanced glycosylation endproducts (RAGE) is a multiligand receptor and known to be implicated in various pathogenic conditions, such as diabetes, inflammatory disorder, Alzheimer disease, and cancer. In this study, the impact of...
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